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The physiology of cardiovascular disease and innovative liposomal platforms for therapy

dc.creatorTorre Amione, Guillermo
dc.date2013
dc.date.accessioned2018-10-19T13:37:34Z
dc.date.available2018-10-19T13:37:34Z
dc.identifier.issn11769114
dc.identifier.doihttp://dx.doi.org/10.2147/IJN.S30599
dc.identifier.urihttp://hdl.handle.net/11285/630612
dc.descriptionHeart disease remains the major cause of death in males and females, emphasizing the need for novel strategies to improve patient treatment and survival. A therapeutic approach, still in its infancy, is the development of site-specific drug-delivery systems. Nanoparticle-based delivery systems, such as liposomes, have evolved into robust platforms for site-specific delivery of therapeutics. In this review, the clinical impact of cardiovascular disease and the pathophysiology of different subsets of the disease are described. Potential pathological targets for therapy are introduced, and promising advances in nanotherapeutic cardiovascular applications involving liposomal platforms are presented. © 2013 Ruiz-Esparza et al, publisher and licensee Dove Medical Press Ltd.
dc.languageeng
dc.relationhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84873663006&doi=10.2147%2fIJN.S30599&partnerID=40&md5=6c3324488146cb10e8ba7c930410b9a8
dc.relationInvestigadores
dc.relationEstudiantes
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0
dc.sourceInternational Journal of Nanomedicine
dc.subjectbile acid sequestrant
dc.subjectcardiovascular agent
dc.subjectCRPPR peptide
dc.subjectdoxorubicin
dc.subjectetanercept
dc.subjectfasudil
dc.subjectfibric acid derivative
dc.subjecthydroxymethylglutaryl coenzyme A reductase inhibitor
dc.subjectliposome
dc.subjectpaclitaxel
dc.subjectphosphatidylserine
dc.subjectprednisolone derivative
dc.subjectrapamycin
dc.subjecttmr 484
dc.subjecttumor necrosis factor inhibitor
dc.subjectunclassified drug
dc.subjectantiproliferative activity
dc.subjectartery intima proliferation
dc.subjectatheroma
dc.subjectatherosclerosis
dc.subjectbreast cancer
dc.subjectcardiovascular disease
dc.subjectcarotid artery disease
dc.subjectcongestive heart failure
dc.subjectcoronary artery bypass graft
dc.subjectcoronary artery disease
dc.subjectdrug distribution
dc.subjectdrug eluting stent
dc.subjectdrug mechanism
dc.subjectdrug targeting
dc.subjectdrug uptake
dc.subjectendocytosis
dc.subjectheart disease
dc.subjectheart failure
dc.subjectheart infarction
dc.subjecthuman
dc.subjecthypercholesterolemia
dc.subjecthypertension
dc.subjectin-stent restenosis
dc.subjectintracoronary infusion
dc.subjectKaposi sarcoma
dc.subjectlifestyle modification
dc.subjectliposomal delivery
dc.subjectnanomedicine
dc.subjectnonhuman
dc.subjectopsonization
dc.subjectoutcome assessment
dc.subjectovary cancer
dc.subjectparticle size
dc.subjectpathophysiology
dc.subjectpercutaneous coronary intervention
dc.subjectprotein expression
dc.subjectrandomized controlled trial (topic)
dc.subjectreview
dc.subjectthrombocyte adhesion
dc.subjectthrombocyte aggregation
dc.subjectcardiovascular disease
dc.subjectliposomes
dc.subjectnanomedicine
dc.subjectnanoparticles
dc.subjecttherapeutics
dc.subjectCardiovascular Diseases
dc.subjectDrug Carriers
dc.subjectFemale
dc.subjectHumans
dc.subjectLiposomes
dc.subjectMale
dc.subjectNanomedicine
dc.subjectNanoparticles
dc.subject.classification7 INGENIERÍA Y TECNOLOGÍA
dc.titleThe physiology of cardiovascular disease and innovative liposomal platforms for therapy
dc.typeArtículo
dc.identifier.volume8
dc.identifier.startpage629
dc.identifier.endpage640
refterms.dateFOA2018-10-19T13:37:34Z


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