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Innovative food processing technologies to enhance the biosynthesis and accumulation of free and bound phenolics in carrots (Daucus carota)
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2020-06-16)
Nowadays, chronic degenerative diseases constitute a major challenge for the health system around the world. These diseases are closely related with a poor-quality diet, which are high in calories, and low in dietary fiber ...
Novel PEGylation and purification strategies for the development of biopharmaceutical products
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2021-08)
This work presents alternative and novel PEGylation reaction and purification strategies to develop biopharmaceutical products using three PEGylated proteins as models: PEGfilgrastim, PEGRNase A and PEGlysozyme. These ...
Feature selection from biological bigdata: identification of significant associations applying multivariate machine learning algorithms to genome-wide association studies (GWAS)
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2019-08)
Crohn's Disease (CD) is a type of Inflammatory Bowel Disease (IBD) affecting the gastrointestinal tract with diverse symptoms. At present, Genome-Wide Association Studies (GWAS) have discovered over 140 genetic loci ...
In-building measurement-based radio propagation modeling using a geostatistical interpolation technique
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2022-11-11)
Channel modeling can enhance communication efficiency through an accurate design to deliver higher quality to mobile users inside buildings. Clear processes and methodologies that can provide a high level of confidence in ...
Pharmacokinetic-pharmacodynamic evaluation of a fraction with a neuroprotective activity of Tagetes lucida
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2022-12-05)
Tagetes lucida has been widely used as a folk remedy in illnesses associated with the central nervous system (CNS) and inflammatory ailments. Among the compounds that stand out in the plant against these conditions are ...
Optimal location-allocation of specialized healthcare service across public hospital networks
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2016-01-01)
In this thesis, we propose a location-allocation model for a specialized diagnostic service that requires costly diagnostic equipment such as MRI, CT, PET/CT, and Digital Mammography in a segmented public healthcare system. ...
Closing the gap on affordable real-time very low resolution face recognition for automated video surveillance
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2022-12-05)
Public and private security is a worldwide problem where efficient and automated video-surveillance technologies have a lot of potential. In an emerging country like Mexico, a functional real-time automated video-surveillance ...
3D printed tumor on chips for the culture and maturation of heterotypic cancer spheroids as a platform for drug testing
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2022-12-05)
The recapitulation of cancer environment in tumor-on-chip systems will greatly contribute to accelerate cancer studies in the fronts on fundamental research, pharmacological testing of new therapeutic compounds, and ...
Triborheological analysis of reconstituted gastrointestinal porcine mucus / chitosan:TPP nanoparticles system for studying mucoadhesion under different pH conditions
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2022-12-05)
The use of biodegradable polymers as vehicles for administration and long-term release of drugs has great relevance in the delivery of new generation therapeutic agents, such as: amino acids, peptides, proteins, antibodies, ...
Effect of osmotic conditions and germination time on the content and profile of glucosinolates, carotenoids and phenolic compounds in kale, and their antioxidant and anti-inflammatory properties
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2022-06-15)
In the past years, abiotic stresses such as saline soaking and the exogenous application of phytohormones such as methyl jasmonate (MeJA) have been studied as an effective tool to improve the accumulation of bioactive ...