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Novel bioengineering strategies for the recovery and purification of PEGylated lysozyme conjugates: in situ ATPS and affinity chromatography

dc.contributor.advisorRito Palomares, Marco Antonio
dc.contributor.advisorMayolo Deloisa, Karla Patricia
dc.contributor.advisorGonzález Valdez, José Guillermo
dc.contributor.authorMejía Manzano, Luis Alberto
dc.creatorMejía Manzano, Luis Alberto; 375359es_MX
dc.date.accessioned2017-10-11T16:03:01Z
dc.date.available2017-10-11T16:03:01Z
dc.date.issued2017-07-13
dc.identifier.urihttp://hdl.handle.net/11285/627931
dc.description.abstractPEGylation is the modification of therapeutic proteins with polyethylene glycol (PEG) with the goal of improving their bioavailability and effectivity in the organism. During the PEGylation process, proteins with different degrees of PEGylation and positi
dc.format.mediumTextoes_MX
dc.language.isoeng
dc.publisherInstituto Tecnológico y de Estudios Superiores de Monterrey
dc.relation.isFormatOfversión publicadaes_MX
dc.relation.isreferencedbyREPOSITORIO NACIONAL CONACYT
dc.rightsopenAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0*
dc.subject.classificationINGENIERÍA Y TECNOLOGÍA; CIENCIAS TECNOLÓGICAS; INGENIERÍA Y TECNOLOGÍA QUÍMICAS; POLIPÉPTIDOS Y PROTEÍNASes_MX
dc.subject.lcshTecnología / Technology
dc.subject.lcshTheory and practice of education--Higher education—Preparation of theseses_MX
dc.titleNovel bioengineering strategies for the recovery and purification of PEGylated lysozyme conjugates: in situ ATPS and affinity chromatography
dc.typeTesis Doctorado / doctoral Thesis
thesis.degree.levelDoctor in Biotechnologyen
dc.contributor.committeememberAsenjo de Leuze, Juan A.en
dc.contributor.committeememberParra Saldívar, Robertoen
thesis.degree.disciplineSchool of Engineering and Sciencesen
thesis.degree.nameDoctorado en Biotecnologíaen
dc.subject.keywordPEGylated proteins
dc.subject.keywordPEGylation
dc.subject.keywordin situ ATPS
dc.subject.keywordHeparin Affinity Chromatography
dc.subject.keywordSimulation
dc.subject.keywordMono-PEGylated lysozyme
dc.subject.keywordOptimization
dc.subject.keywordCovalent immobilization
thesis.degree.programCampus Monterreyen
dc.subject.disciplineIngeniería y Ciencias Aplicadas / Engineering & Applied Sciencesen
dc.audience.educationlevelInvestigadores/Researchers
refterms.dateFOA2018-03-07T08:13:03Z
dc.identificator7
dc.identificator33
dc.identificator3303
dc.identificator230418


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