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Implantable platform with in-situ vascularization and localized immunosuppression for allogeneic cell transplantation.
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2021-04)
Allogeneic islet transplantation for diabetes management faces the challenge of preventing immune rejection while maintaining enough graft oxygenation for proper metabolic function. Islet encapsulation within membranes ...
Corneal endothelium produced by tissue engineering
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2020-12-14)
Engineered corneal endothelium (ECE) must assure cell morphology and physiology. To do so, a biocompatible, transparent, scaffold is the best option. The purpose of this thesis is to produce an ECE with a collagen scaffold ...
Development of novel polymer-protein conjugates and characterization of chromatographic supports
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2021-06-10)
Protein versatility has positioned them as a high-value biotechnological product. Among protein applications, its use as a therapeutic agent is highlighted. However, some therapeutic proteins need a modification process ...