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Modeling the effects of exercise on blood glucose concentration level and their compensation with the design of a feedforward predictive control strategy.

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Abstract

Diabetes Mellitus disease is the principle cause of death in Mexico since year 2000, especially for the different complications that arise from this illness, such as heart, kidney, and hepatic failure. The principal risk factors that highly alter glucose concentration level in diabetic patients are carbohydrates consumption and prolonged exercise. This is due to a null insulin production in the Langerhans cells or to an increase of insulin resistance in the biochemical receptors of the body. Today's treatments for controlling blood glucose level, which are the injection of insulin boluses and the following of a special nutritional regimen, are very susceptible to human errors, so there is a latent possibility that damage can be done to the patients health. Therefore, it is indispensable to regulate glucose concentration level in an automatic form. In this research area, the scientist have mainly developed control strategies that impede glucose level to increase when the patients has a meal; successful results have been reported. However, no investigation was found concerned with the regulation of glucose level when physical activity is done, and which is an important factor, since prolonged exercise can cause hypoglycemic episodes that can lead to severe injuries in the person, even death.

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