Show simple item record

dc.contributor.advisorMagaña Aguirre, Jonathan Javier
dc.contributor.authorFarah, Sonia Jihad
dc.date.accessioned2023-12-05T22:14:37Z
dc.date.available2023-12-05T22:14:37Z
dc.date.issued2023
dc.identifier.citationFarah, S. J. (2023). "Evaluation of the Effect of Ellagic Acid on Muscle Differentiation"(Master's thesis). Tecnológico de Monterrey.es_MX
dc.identifier.urihttps://hdl.handle.net/11285/651608
dc.descriptionhttps://orcid.org/0000-0003-4399-4618es_MX
dc.description.abstractThis thesis investigates the potential impact of ellagic acid (EA), a polyphenol present in various fruits and nuts, on in vitro muscle differentiation using the C2C12 mouse myoblast cell line. Muscle differentiation is a complex process involving specific genes and signaling pathways, and recent interest in natural compounds, including EA, has sparked exploration into their effects on this critical physiological process. The study aims to determine effective and non-cytotoxic concentrations of EA, analyze myotube formation, and evaluate the expression of key differentiation markers at both gene and protein levels. The findings reveal the safety and efficacy of EA at specific concentrations. Morphological, as well as gene and protein expression analyses provide insights into the initiation and progression of myoblast differentiation, emphasizing EA's positive impact on essential markers. This research not only confirms the initial hypothesis but also positions EA as a potent promoter of muscle differentiation, offering potential therapeutic applications for muscle regeneration and disorders. Future directions include exploring EA in pathological muscle conditions and addressing challenges in oral bioavailability through innovative delivery strategies. The ongoing journey into the unknown seeks to deepen our understanding of EA and its broader implications for muscle health.es_MX
dc.format.mediumTextoes_MX
dc.language.isoenges_MX
dc.publisherInstituto Tecnológico y de Estudios Superiores de Monterreyes_MX
dc.relation.isFormatOfacceptedVersiones_MX
dc.rightsopenAccesses_MX
dc.rights.urihttp://creativecommons.org/licenses/by/4.0es_MX
dc.subject.classificationINGENIERÍA Y TECNOLOGÍAes_MX
dc.subject.lcshSciencees_MX
dc.titleEvaluation of the effect of ellagic acid on muscle differentiationes_MX
dc.typeTesis de Maestría / master Thesises_MX
dc.contributor.departmentSchool of Engineering and Scienceses_MX
dc.contributor.committeememberBorbolla-Jiménez, Fabiola V.
dc.contributor.committeememberCalderón Oliver, Mariel
dc.identifier.orcidhttps://orcid.org/0009-0000-3796-9278es_MX
dc.subject.keywordEllagic acides_MX
dc.subject.keywordmuscle differentiationes_MX
dc.subject.keywordmyoblastes_MX
dc.subject.keywordmyotubeses_MX
dc.subject.keyworddifferentiation markerses_MX
dc.subject.keywordmuscle regenerationes_MX
dc.contributor.institutionCampus Monterreyes_MX
dc.contributor.catalogerdnbsrpes_MX
dc.description.degreeMaestría en Ciencias con Especialidad en Biotecnologíaes_MX
dc.identifier.cvu1185447es_MX
dc.date.accepted2023-11-21
dc.audience.educationlevelInvestigadores/Researcherses_MX
dc.identificator7es_MX


Files in this item

Thumbnail
Thumbnail
Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record

openAccess
Except where otherwise noted, this item's license is described as openAccess