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dc.contributor.advisorZúñiga, Alex Elíasen_US
dc.contributor.advisorOlivera Trejo, Danielen_US
dc.contributor.authorBenjamin de Jesus, Benjamín Evanien_US
dc.date.accessioned2018-05-29T13:42:14Z
dc.date.available2018-05-29T13:42:14Z
dc.date.issued2018-05-14
dc.identifier.urihttp://hdl.handle.net/11285/629921
dc.description.abstractAdditive manufacturing by Digital Light Processor stereolithography (DLP-SLA) has shown a great potential to create high-density microfluidic devices due to it offers high resolution and relatively low-cost. In this work, the fabrication of 3D printed coaxial electrospray sources with a high density of emitters are reported by using DLP-SLA technology. The 3D printed electrospray sources have also proven to work correctly as a source of microencapsulation. To accomplish the objectives of the study, it was addressed in three sections primarily. First, the influence of the involved parameters on the final properties of printed microchannels was evaluated by the analysis and characterization of this promising additive manufacturing technology. Second, based on its maximum printing capabilities, multiplexed electrospray sources were designed. To manufacture suitable channels with diameters up to 160 µm, it was key to establish the smallest dimensions of the new devices, which were successfully printed with 41 and 57 coaxial emitters respectively. Finally, Vitamin D and alginate hydrogel were used to produce core-shell microparticles as an initial exploration in the encapsulation of biomedical substances via coaxial electrospraying. The accurate encapsulation was dependent on the flow rate, applied voltages, and mainly on the concentration of alginate solution.
dc.language.isoengen_US
dc.publisherInstituto Tecnológico y de Estudios Superiores de Monterreyesp
dc.rightsRestricted Accessen_US
dc.titleNew Generation of 3D printed electrospray sources for microencapsulation in biomedical applicationsen_US
dc.typeTesis de Maestríaesp
thesis.degree.levelMaestro en Ciencias con especialidad en Sistemas de Manufacturaen_US
dc.contributor.committeememberMartínez Romero, Oscaren_US
dc.contributor.committeememberGarcía López, Erikaen_US
thesis.degree.disciplineEscuela de Ingeniería y Cienciasen_US
thesis.degree.nameMaestría en Ciencias con especialidad en Sistemas de Manufacturaen_US
dc.subject.keywordMultiplexeden_US
dc.subject.keywordCoaxialen_US
dc.subject.keywordElectrosprayen_US
dc.subject.keywordEncapsulationen_US
dc.subject.keyword3D Printingen_US
thesis.degree.programCampus Monterreyen_US
dc.subject.disciplineIngeniería y Ciencias Aplicadas / Engineering & Applied Sciencesen_US
refterms.dateFOA2018-05-29T13:42:15Z
html.description.abstract<html> <head> <title></title> </head> <body> <p>Additive manufacturing by Digital Light Processor stereolithography (DLP-SLA) has shown a great potential to create high-density microfluidic devices due to it offers high resolution and relatively low-cost. In this work, the fabrication of 3D printed coaxial electrospray sources with a high density of emitters are reported by using DLP-SLA technology. The 3D printed electrospray sources have also proven to work correctly as a source of microencapsulation. To accomplish the objectives of the study, it was addressed in three sections primarily. First, the influence of the involved parameters on the final properties of printed microchannels was evaluated by the analysis and characterization of this promising additive manufacturing technology. Second, based on its maximum printing capabilities, multiplexed electrospray sources were designed. To manufacture suitable channels with diameters up to 160 &#181;m, it was key to establish the smallest dimensions of the new devices, which were successfully printed with 41 and 57 coaxial emitters respectively. Finally, Vitamin D and alginate hydrogel were used to produce core-shell microparticles as an initial exploration in the encapsulation of biomedical substances via coaxial electrospraying. The accurate encapsulation was dependent on the flow rate, applied voltages, and mainly on the concentration of alginate solution.</p> </body> </html>en_US


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