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Feature selection from biological bigdata: identification of significant associations applying multivariate machine learning algorithms to genome-wide association studies (GWAS)
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2019-08)
Crohn's Disease (CD) is a type of Inflammatory Bowel Disease (IBD) affecting the gastrointestinal tract with diverse symptoms. At present, Genome-Wide Association Studies (GWAS) have discovered over 140 genetic loci ...
Optimal location-allocation of specialized healthcare service across public hospital networks
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2016-01-01)
In this thesis, we propose a location-allocation model for a specialized diagnostic service that requires costly diagnostic equipment such as MRI, CT, PET/CT, and Digital Mammography in a segmented public healthcare system. ...