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Novel bioengineering strategies for the recovery and purification of PEGylated lysozyme conjugates: in situ ATPS and affinity chromatography
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2017-07-13)
PEGylation is the modification of therapeutic proteins with polyethylene glycol (PEG) with the goal of improving their bioavailability and effectivity in the organism. During the PEGylation process, proteins with different ...
Principles to Automate Inventive Problem Solving Based on Dialectical Negation, Assisted by Evolutionary Algorithms and TRIZ
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2011-01-05)
An inventive problem (IP) can be defined as a human perception of a situation that has to be changed, but with at least one obstacle which impedes achievement of the desired goal. In practice, they are solved generally ...