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Controlled drug delivery strategies: Advances on the synthesis and molecular dynamics of dendrimers, and optimization of liposomes preparation by Dual Asymmetric Centrifugation
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2017-12-01)
In early phase of drug development, New Chemical Entities (NCEs) are used as highly active drugs, with limited availability, and high cost. This study presents two alternatives of drug delivery systems, site-specific ...
Engineering mammalian-specific post-translational modifications in plant-derived proteins: phosphorylation and Mucin-type O-glycosylation as a challenge.
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2018-12-14)
Expression of economically relevant plant-derived recombinant proteins in alternative expression platforms, especially plant expression platforms, has gained significant interest in recent years, due to the possibility to ...
Platelets contribute to hemostasis, thrombosis, and allergic airway inflammation via Munc13-4-dependent secretion
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2018-11-01)
With over 200 million affected individuals, asthma is the most common chronic respiratory disease in the world. One old observation that begs an explanation is the relationship between platelets, their activation, and the ...
Characterization of the skin secretions of Dryophytes arenicolor and identification of Arenin, a novel Kunitz-like polypeptide
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2018-12)
Zootherapy is the treatment of human ailments with remedies made from animals and their products. Despite its prevalence in the traditional medical practices worldwide, research on this phenomenon has often been neglected ...